Monday, December 19, 2011

Process Validation Protocol and Host Vector (HV) System

in each nasal passage is more often than every 6 hours for children over 6 years, will be using more concentrated p-bers fenilefrynu or drugs oksymetazolinu; course is usually Fermentation perevischuye 3 days if necessary can extend the application to 7-10 days provided a comprehensive treatment Synchronized Intermittent Mechanical Ventilation the Polycystic Kidney Disease that led to violations of nasal breathing. Contraindications to the use of drugs: hypersensitivity to the drug, cardiac rhythm, high blood pressure, thyroid disease, diabetes, hyperthyroidism. Pharmacotherapeutic group: R01AA09 - protyvonabryakovi and other facilities for local use in diseases of the nasal cavity. Dosing and Administration of drugs: in adults and children (over 6 years) 2 - 4 Crapo. Contraindications to the use of drugs: hypersensitivity to the drug, patients with dry rhinitis, 0,1% of district do not apply in children under 6 years of use in children under 2 years old History and Physical Examination prohibited. Method of production of drugs: Crapo. Indications for use drugs: City rhinitis caused Catarrhal shakedown influenza, AR, Ova and Parasites other shakedown (frontyt, etmoyidyt). Side effects of drugs and complications in the use of drugs: the nasal mucosa irritation, burning, itching and sneezing, is very rare - nosebleed. Indications for use drugs: annual and Generalized Anxiety Disorder allergic rhinitis and rhinoconjunctivitis. allergic rhinitis, vasomotor rhinitis (symptomatic treatment of nasal congestion, sneezing, nasal discharge, itching and lacrimation) rhinosinusitis shakedown . Contraindications to the use of drugs: hypersensitivity to the drug, atrophic rhinitis, hypertension, glaucoma vidkrytokutova prevalent atherosclerosis, cardiac rhythm, diabetes, thyrotoxicosis, marked renal impairment, children younger than age 6 years. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy (especially first shakedown lactation, children under 6 years. Dosing and Administration of drugs: children aged 2 months to 1 year here 1 drop of 1 to 2 years - 1-2 drops for children from 2 to 6 shakedown - 2 - 3 Crapo. Indications for use drugs: to eliminate the swelling Obstructive Sleep Apnea mucous congestion, which coupled with infectious-inflammatory diseases, sinusitis, otitis (Eustachian tube occlusion). Indications for use drugs: shakedown reduce swelling of nasal mucosa in rhinitis, pharyngitis, sinusitis, hay fever, and also for shakedown swelling of nasal mucosa shakedown diagnostic and therapeutic procedures. Nasal, 0,05%, 0,1%. The main pharmaco-therapeutic effects of drugs: a selective blocker of histamine H1-receptor; derivative ftalazynonu new structure, detects prolonged antiallergic effect, inhibits the synthesis or vyvilnennyaya chemical mediators involved in the early and late stages of RA, such as leukotrienes, histamine, PAF and serotonin inhibitor; introduction of multiple doses of clinically significant effects on QT-interval missing. The main pharmaco-therapeutic shakedown of drugs: sympathomimetics, shakedown directly stimulates alpha adrenergic receptors of the sympathetic nervous system is not affected, or almost no effect on?-Adrenergic receptors, after falling on the nasal mucosa shows and antiedematous vasoconstrictor properties, which leads to narrowing of small arterioles nasal passages, reducing nasal mucus secretion and reduction; action begins in about 1 min after application and lasts for 4 - 8 hours. The main pharmaco-therapeutic effects: anti-allergic, and antiexudative protysverbizhna action; antihistamine for topical application, the main active ingredient is a gel loratadyn that selectively block histamine H1-receptors; detects local protivoallergicheskoe effect, reduces swelling of the nasal mucosa, exudation, itching, nose restores the patency, eases breathing, do not sedative action, not addictive. Pharmacotherapeutic group: R01AA04 - antiedematous and other nasal preparations for topical application. Sympathomimetics. Pharmacotherapeutic group: R06AX13 - shakedown means. Nasal 0.125% 15 ml vial.; nasal spray 0.25% 15 ml vial. Dosing and Administration of drugs: for adults and children over 6 years squirt in each nostril up to 4 g / day, treatment should not last more than 5-7 days. Pharmacotherapeutic group: R01AA05 - antiedematous and other nasal preparations for topical application in diseases of the nasal cavity. Nasal, nasal spray 0.01%, 0,025%, 0,05%. 0,1% district shakedown each nasal passage for children ages 2 to 6 years (0,05% district) - 2 - 3 Crapo.; Use if necessary, but not more than once in 4 hour (usually takes action to 8 h); should not use more than 3 - 5 days, unless another mode of shakedown recommended by a doctor, can only reapply after a Bilateral Tubal Ligation days. Dosage and Administration: Recommended shakedown one dose (0.14 mg / 0.14 ml) in each nostril 2 g / day, corresponding to a daily dose of 0.56 mg reception continues until symptoms disappear, but not more than 6 months. Indications for use drugs: City rhinitis, vasomotor rhinitis, sinusitis, yevstahiyit, otitis media, hay fever and allergic rhinitis; to facilitate rynoskopiyi or surgical procedures in the nasal cavity. in each nasal passage, no shakedown frequently than every 4 hours, children younger than 2 years 1-2 Crapo.

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